Classic Southern Meatloaf with Tomato Sauce is a comforting dish that brings rich flavors and nostalgia to the table. Perfect for family dinners or gatherings, this meatloaf is not only satisfying but also incredibly versatile. The combination of ground beef, vibrant vegetables, and a sweet & tangy tomato sauce makes it stand out in any meal lineup. Whether served with mashed potatoes or on a sandwich the next day, this classic will quickly become a favorite.
Why You’ll Love This Recipe
- Flavorful: The blend of onions, bell peppers, and spices creates a deliciously savory taste.
- Easy Preparation: With simple steps and common ingredients, this dish is perfect for cooks of all levels.
- Versatile Serving Options: Enjoy it as an entree or as leftovers in sandwiches—great for any occasion!
- Comfort Food Classic: This hearty meal evokes feelings of nostalgia and warmth, making it ideal for family gatherings.
- Healthy Twist: Using lean ground beef ensures you get a nutritious meal without sacrificing flavor.
Tools and Preparation
To create your Classic Southern Meatloaf with Tomato Sauce efficiently, having the right tools is essential.
Essential Kitchen Tools
- Mixing bowl
- Broiler pan
- Measuring cups
- Measuring spoons
- Whisk or fork
Why These Tools Matter
- Mixing bowl: A large bowl allows you to combine all ingredients without spilling.
- Broiler pan: This tool helps cook the meatloaf evenly while allowing grease to drain away.
- Measuring cups and spoons: Precise measurements are crucial for achieving the perfect flavor balance.
- Whisk or fork: Useful for beating eggs thoroughly and mixing ingredients smoothly.
Ingredients
Classic meatloaf seasoned with onions, bell peppers and a sweet & tangy tomato sauce.
For the Meatloaf
- 2½ lb. ground beef (80/20 or 73/27)
- ¾ cup chopped yellow onions
- ¾ cup chopped green bell peppers
- 1½ cups bread crumbs (seasoned or not seasoned; traditional or Panko)
- 2 whole eggs (lightly beaten)
- 3 tablespoons Worcestershire sauce
- 1 tablespoon dry mustard
- 1 teaspoon garlic powder
- 1 teaspoon salt
- ½ teaspoon black pepper
For the Tomato Sauce
- 3 cups ketchup
- ⅓ cup brown sugar
- 1 teaspoon dry mustard
- 2 tablespoons Worcestershire sauce
Instructions:
1. Combine sauce ingredients in a medium bowl and set aside.
2. Lightly spray broiler pan; set aside.
3. Lightly beat eggs in a bowl; set aside.
4. Preheat oven to 375°.
5. Combine all meatloaf ingredients into big bowl; with clean hands, mix ingredients until combined; do NOT overwork the meat.
6. Place beef mixture onto counter and shape into a rectangular loaf.
7. Place on lightly oiled broiling pan and bake uncovered for 30-45 minutes, or until meat has reached 150° internal temperature.
8. After it has reached 150ºF, remove from oven, pour some tomato sauce over the top and return to oven.
9. Bake until internal temperature reaches 160ºF and tomato sauce is thickened.
10. Remove from oven; allow meatloaf to sit for a few minutes, then slice and serve.
Servings: 8 1-inch slices
Prep Time: 15 minutes
Cook Time: 60 minutes
Total Time: 75 minutes
Course: Entree
Cuisine: American

How to Make Classic Southern Meatloaf with Tomato Sauce
Step 1: Prepare the Tomato Sauce
Combine all sauce ingredients (ketchup, brown sugar, dry mustard, Worcestershire sauce) in a medium bowl. Stir until thoroughly mixed and set aside.
Step 2: Prepare the Broiler Pan
Lightly spray your broiler pan with cooking spray to prevent sticking. Set it aside for later use.
Step 3: Beat the Eggs
In a small bowl, lightly beat two eggs using a whisk or fork until blended smoothly. Set this bowl aside.
Step 4: Preheat Your Oven
Preheat your oven to 375°F (190°C) to ensure it’s ready when your meatloaf is prepared.
Step 5: Mix the Meatloaf Ingredients
In a large mixing bowl, combine the ground beef, chopped onions, chopped bell peppers, bread crumbs, beaten eggs, Worcestershire sauce, dry mustard, garlic powder, salt, and black pepper. Use clean hands to mix everything together gently until just combined—avoid overworking the meat.
Step 6: Shape the Meatloaf
Transfer the mixed beef mixture onto a clean surface. Shape it into a rectangular loaf about one inch thick to ensure even cooking.
Step 7: Bake the Meatloaf
Place your shaped meatloaf onto the prepared broiler pan. Bake uncovered in your preheated oven for about 30-45 minutes or until it reaches an internal temperature of 150°F (65°C).
Step 8: Add Tomato Sauce Topping
Once cooked through at 150°F (65°C), remove your meatloaf from the oven. Pour some of your prepared tomato sauce over the top evenly before returning it to bake.
Step 9: Final Baking
Continue baking until the internal temperature of your meatloaf reaches 160°F (71°C) and you’ve achieved that thickened tomato sauce look on top—this should take another few minutes.
Step 10: Serve
Remove your beautifully baked meatloaf from the oven once done! Allow it to rest for several minutes before slicing into generous portions. Serve warm with additional tomato sauce if desired!
Enjoy your delicious Classic Southern Meatloaf with Tomato Sauce!
How to Serve Classic Southern Meatloaf with Tomato Sauce
Serving Classic Southern Meatloaf with Tomato Sauce can elevate your dining experience. Here are some delicious ways to enjoy this hearty dish.
With Creamy Mashed Potatoes
- Creamy mashed potatoes pair perfectly, absorbing the flavorful sauce and adding a comforting texture.
On a Bed of Greens
- Serve slices of meatloaf on a bed of mixed greens for a fresh contrast that lightens the meal.
With Roasted Vegetables
- Roasted vegetables add color and nutrition. Try carrots, Brussels sprouts, or green beans for a balanced plate.
As a Sandwich
- Transform leftovers into a tasty meatloaf sandwich. Simply add your choice of condiments and toppings between two slices of bread.
With Coleslaw
- A side of coleslaw offers crunch and tang, balancing the richness of the meatloaf.
Topped with Fried Egg
- For a breakfast twist, top your slice with a sunny-side-up egg for a delightful combination of flavors.
How to Perfect Classic Southern Meatloaf with Tomato Sauce
To achieve the best results when making Classic Southern Meatloaf with Tomato Sauce, consider these helpful tips.
- Use Fresh Ingredients: Fresh vegetables and quality ground beef enhance flavor and texture.
- Don’t Overmix: Mix the ingredients until just combined to keep the meatloaf tender.
- Adjust Seasonings: Feel free to tweak spices according to your taste preferences for a personalized touch.
- Let it Rest: Allowing the meatloaf to rest after baking helps retain its juices and makes slicing easier.
- Use Lean Ground Beef: Opt for 80/20 or 73/27 ground beef for the right balance of flavor and moisture.
- Experiment with Toppings: Try different sauces or glazes to find your favorite flavor combination.

Best Side Dishes for Classic Southern Meatloaf with Tomato Sauce
Pairing side dishes with your meatloaf can enhance the overall meal. Here are some perfect accompaniments to consider:
- Creamed Spinach: This rich dish provides a creamy texture that complements the savory meatloaf.
- Baked Sweet Potatoes: Their natural sweetness balances the savory flavors of the meatloaf.
- Cornbread: A classic Southern side, cornbread adds a slightly sweet element that pairs well.
- Green Beans Almondine: The crunch from almonds complements the softness of the meatloaf nicely.
- Macaroni and Cheese: This comfort food classic is always a hit, offering cheesy goodness alongside your main dish.
- Garlic Bread: Perfect for soaking up extra tomato sauce, garlic bread adds another layer of flavor to your meal.
- Potato Salad: A cool potato salad provides a refreshing contrast to the warm meatloaf.
- Roasted Asparagus: Lightly seasoned roasted asparagus brings brightness and flavor to your plate.
Common Mistakes to Avoid
When making Classic Southern Meatloaf with Tomato Sauce, it’s easy to make a few common mistakes. Here are some tips to help you achieve the best results.
- Bold Ingredients: Using low-quality meat can affect the flavor and texture of your meatloaf. Choose fresh, good-quality ground beef for better taste.
- Bold Overmixing: Mixing the ingredients too much can lead to a tough meatloaf. Combine everything gently until just mixed to keep it tender.
- Bold Skipping the Resting Time: Cutting into the meatloaf right away can cause it to fall apart. Let it rest for a few minutes after baking for better slicing.
- Bold Ignoring Temperature Checks: Not checking the internal temperature can result in undercooked meatloaf. Use a meat thermometer to ensure it reaches 160°F.
- Bold Not Using Enough Seasoning: A lack of seasoning can make your meatloaf bland. Make sure to season generously with salt, pepper, and other spices.
Refrigerator Storage
- Store leftovers in an airtight container.
- Meatloaf will last 3-4 days in the refrigerator.
- For best quality, wrap it tightly in plastic wrap before placing it in a container.
Freezing Classic Southern Meatloaf with Tomato Sauce
- Freeze individual slices or whole loaves for convenience.
- Wrap tightly in aluminum foil or freezer-safe bags.
- Meatloaf can be frozen for up to 3 months.
Reheating Classic Southern Meatloaf with Tomato Sauce
- Oven: Preheat oven to 350°F and cover with foil; bake until heated through (about 20-30 minutes).
- Microwave: Place on a microwave-safe plate; heat on medium power in 1-minute intervals until warm.
- Stovetop: Heat slices in a skillet over medium heat, adding a splash of broth or water if needed to avoid drying out.

Frequently Asked Questions
What is the best way to shape Classic Southern Meatloaf?
To shape your meatloaf, place the mixture on a clean countertop and form it into a rectangular loaf. This shape helps it cook evenly.
Can I use other meats in Classic Southern Meatloaf with Tomato Sauce?
Yes! You can use ground chicken, turkey, or even lamb as alternatives for ground beef while keeping the flavors intact.
How do I keep my Classic Southern Meatloaf from getting soggy?
To prevent sogginess, avoid adding too much wet ingredients and ensure proper mixing without overworking the meat.
What sides pair well with Classic Southern Meatloaf?
Classic Southern Meatloaf goes great with mashed potatoes, green beans, or cornbread for a complete meal.
Conclusion
Classic Southern Meatloaf with Tomato Sauce is not only hearty and comforting but also versatile. Feel free to customize this recipe by adding your favorite vegetables or spices. It’s perfect for family dinners or meal prep!
Classic Southern Meatloaf with Tomato Sauce
Classic Southern Meatloaf with Tomato Sauce is a culinary delight that combines comfort and flavor in every bite. This hearty dish features a blend of ground beef, fresh vegetables, and a rich tomato sauce that creates a perfect symphony of savory goodness. Whether you’re gathering for a family dinner or preparing meals for the week, this meatloaf is versatile enough to be enjoyed in various ways—served hot with mashed potatoes or transformed into a delicious sandwich for lunch. Its easy preparation makes it accessible for cooks of all skill levels, while its nostalgic flavors will remind you of home-cooked meals shared with loved ones.
- Prep Time: 15 minutes
- Cook Time: 60 minutes
- Total Time: 1 hour 15 minutes
- Yield: Serves 8
- Category: Entree
- Method: Baking
- Cuisine: American
Ingredients
- 2½ lb ground beef (80/20 or 73/27)
- ¾ cup chopped yellow onions
- ¾ cup chopped green bell peppers
- 1½ cups bread crumbs
- 2 whole eggs (lightly beaten)
- 3 tablespoons Worcestershire sauce
- 3 cups ketchup
- ⅓ cup brown sugar
Instructions
- Preheat your oven to 375°F (190°C).
- In a medium bowl, mix together ketchup, brown sugar, dry mustard, and Worcestershire sauce; set aside.
- Lightly spray a broiler pan with cooking spray.
- In a large mixing bowl, combine ground beef, onions, bell peppers, bread crumbs, beaten eggs, Worcestershire sauce, dry mustard, garlic powder, salt, and black pepper. Mix gently until just combined.
- Shape the mixture into a rectangular loaf and place it on the prepared broiler pan.
- Bake uncovered for about 30-45 minutes until the internal temperature reaches 150°F (65°C).
- Pour some of the prepared tomato sauce over the top and return to the oven until it reaches an internal temperature of 160°F (71°C) and the sauce thickens.
- Let rest for several minutes before slicing and serving.
Nutrition
- Serving Size: 1 slice (approximately 120g)
- Calories: 290
- Sugar: 10g
- Sodium: 540mg
- Fat: 18g
- Saturated Fat: 7g
- Unsaturated Fat: 9g
- Trans Fat: 0g
- Carbohydrates: 19g
- Fiber: 1g
- Protein: 18g
- Cholesterol: 75mg



